A toolkit of methods of development-focused health technology assessment

Abstract Health technology assessment conducted to inform decisions during development (development-focused or DF-HTA) has a number of distinct features compared with HTA reimbursement and usage decisions. In particular, there are broad range be informed related the technology; multiple markets decision makers considered; limited (and developing) evidence base; constrained resources for analysis. These impact upon methods adopted by analysts. this paper, we (i) set out DF-HTA against timeline development; (ii) provide examples methods’ use; (iii) explain how they have been adapted as result DF-HTA. We present toolkit analysts working developers medical technologies. Three categories described: literature review, stakeholder consultation, analytic modeling. Literature review consultation often used fill gaps. Decision modeling is synthesize available alongside plausible assumptions about price performance requirements. Methods increase in formality complexity base progresses more assessment. hope will conjunction framework presented our earlier article order improve clarity appropriateness also seek contribute continuing dialogue nature of, best approach to,